The information in this application represents the testing protocols used at Wieslab. If you use other laboratories, please check the methods and reference ranges that are used there.
When do I order an autoantibody analysis?
On suspicion of chronic or acute inflammatory diseases with the presence of autoantibodies, in particular to confirm or exclude the diagnosis, and to assess disease activity, prognosis and effect of treatment of certain diseases.
On suspicion of an autoimmune disease it should be noted that findings of autoantibodies can only be used to support the diagnosis, as autoantibodies may occur without a disease or as a transient phenomenon during infection. A positive or negative result of a test can therefore not be used for a diagnosis, if there are no defined clinical disease criteria. In some diseases it may be appropriate to monitor the concentration of autoantibodies with regard to the development of manifest disease, on other occasions with regard to the assessment of disease activity, prognosis or effect of the treatment.
What should I send?
Take a venous or capillary blood sample in a tube without additive, let the sample clot and centrifuge it. The sample can be kept in a refrigerater while waiting for transport. Send 1-3 ml serum by ordinary mail. This will be enough for one or several analyses. For complement factor C3d, EDTA plasma is also required. Acute analyses should be sent by registered mail, taxi or courier.
What acute analyses are offered?
Acute analyses for anti-GBM and ANCA are performed all days of the year. For analyses on evenings and weekends, please call the laboratory to discuss means of transportation.